Prolonged ICU Stay in Severe and Critically-Ill COVID-19 Patients Who Received Convalescent Plasma Therapy

Autor: Bambang Pujo Semedi, Nadya Noor Ramadhania, Betty Agustina Tambunan, Siprianus Ugroseno Yudho Bintoro, Soedarsono Soedarsono, Cita Rosita Sigit Prakoeswa
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Critical Care Research and Practice, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 2090-1313
DOI: 10.1155/2022/1594342
Popis: Background. Convalescent plasma administration in severe and critically-ill COVID-19 patients have been proven to not provide improvement in patients’ outcome, yet it is still widely used in countries with limited resources due to its high availability and safety. This study aims to investigate its effects on ICU mortality, ICU length of stay (LoS), and improvement of oxygen support requirements. Methods. Data of all severe and critically-ill patients in our COVID-19 ICU was collected retrospectively between May and November 2020. We dichotomized the variables and compared outcome data of 48 patients, who received convalescent plasma to 131 patients, receiving standard of care. Data were analyzed using multiple logistic regression to make prediction models of mortality, length of stay, and oxygen support device requirement. Result. Overall mortality rate in our COVID-19 ICU was 55.3%, with a median overall length of stay of 8 (4–11) days. Less patients that received convalescent plasma presented with the need for mechanical ventilation on ICU admission p
Databáze: Directory of Open Access Journals
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