Application and trend of bioluminescence imaging in metabolic syndrome research

Autor: Shirui Li, Kang Wang, Zeyu Wang, Wenjie Zhang, Zenglin Liu, Yugang Cheng, Jiankang Zhu, Mingwei Zhong, Sanyuan Hu, Yun Zhang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Chemistry, Vol 10 (2023)
Druh dokumentu: article
ISSN: 2296-2646
DOI: 10.3389/fchem.2022.1113546
Popis: Bioluminescence imaging is a non-invasive technology used to visualize physiological processes in animals and is useful for studying the dynamics of metabolic syndrome. Metabolic syndrome is a broad spectrum of diseases which are rapidly increasing in prevalence, and is closely associated with obesity, type 2 diabetes, nonalcoholic fatty liver disease, and circadian rhythm disorder. To better serve metabolic syndrome research, researchers have established a variety of animal models expressing luciferase, while also committing to finding more suitable luciferase promoters and developing more efficient luciferase-luciferin systems. In this review, we systematically summarize the applications of different models for bioluminescence imaging in the study of metabolic syndrome.
Databáze: Directory of Open Access Journals