| Autor: |
Ting Ting Zhu, Li Wu, Xiao Li Wang, Hui Zhu, Xiao Chai Zhu, Qi Gang Zhou, Xiao Liu, Bao Chang Cai |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Journal of Functional Foods, Vol 31, Iss , Pp 104-112 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2017.01.028 |
| Popis: |
Prepared rhubarb is obtained by steaming raw rhubarb with glutinous rice wine. To explore the chemical material basis and functional mechanism of prepared rhubarb, an ultra-performance liquid chromatography-quadrupole-time of flight-mass spectrometry coupled with gray correlation analysis statistical method was developed. Finally, 19 compounds in rat plasma were detected after oral administration of prepared rhubarb decoction. It was found that 9 of them were the original form of compounds in prepared rhubarb, and the other 10 were the relative metabolites. Taking bioeffects-time curves into consideration as well, gray correlation analysis were performed. The ranking of these 19 compounds was given out basing on their respective contribution to the drug bioeffect. Rhein glucuronide was eventually found possessing the highest possibility to be the main active ingredient for treatment of noxious heat with blood stasis syndrome. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Full Text from ScienceDirect