| Autor: |
Yun-Zhi Lin, Ping Xie, Qing-Huai Liu |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Guoji Yanke Zazhi, Vol 14, Iss 8, Pp 1394-1398 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1672-5123 |
| DOI: |
10.3980/j.issn.1672-5123.2014.08.07 |
| Popis: |
AIM: To investigate the effect of low intensity white light irradiation on the retinas of mice.METHODS: Thirty C57BL/6J mice were randomly divided into two groups. The number of the mice in each group was 15. The mice in experimental group received dark adaptation from 5:00p.m. to 6:00p.m.,and then exposed to LED white light from 6:00p.m. to 7:00p.m. everyday for a month. At 1, 3, 7, 14 and 30d after the beginning, we examed the histology of mice retinas, calculated the thickness of outer nuclear layer(ONL),inner nuclear layer(INL)and analyzed electrophysiology of mice.RESULTS:One month after experiment, compared to the control group, the latency of Rod-R a wave of the mice in experimental group significantly prolonged, the amplitude of Cone-R b wave of the mice in experimental group significantly decreased and the latency of b wave of the mice in experimental group significantly prolonged(PCONCLUSION: 100lux low intensity white light could give rise to the impairment of the retinal functions in dark-adapted mice. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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