| Autor: |
Manuel Rey-Funes, Ignacio M. Larrayoz, Daniela S. Contartese, Manuel Soliño, Anibal Sarotto, Martín Bustelo, Martín Bruno, Verónica B. Dorfman, César F. Loidl, Alfredo Martínez |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-017-07294-6 |
| Popis: |
Abstract Ocular and periocular traumatisms may result in loss of vision. Hypothermia provides a beneficial intervention for brain and heart conditions and, here, we study whether hypothermia can prevent retinal damage caused by traumatic neuropathy. Intraorbital optic nerve crush (IONC) or sham manipulation was applied to male rats. Some animals were subjected to hypothermia (8 °C) for 3 h following surgery. Thirty days later, animals were subjected to electroretinography and behavioral tests. IONC treatment resulted in amplitude reduction of the b-wave and oscillatory potentials of the electroretinogram, whereas the hypothermic treatment significantly (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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