| Autor: |
Matthew P. Parsons, Matthieu P. Vanni, Cameron L. Woodard, Rujun Kang, Timothy H. Murphy, Lynn A. Raymond |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms11251 |
| Popis: |
Huntington disease (HD) has been linked via biochemical uptake assays to impaired glutamate clearance and resultant excitotoxicity. Here, utilizing a fluorescent reporter, the authors measure real-time glutamate dynamics in mouse model HD brain slices and find normal or even accelerated glutamate clearance. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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