Mechanical prosthetic valve thrombosis after ChAdOx1-nCoV-19 vaccination: A case report
Autor: | Akash Jain, Varun Marimuthu, Nagamani Alur |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | IHJ Cardiovascular Case Reports, Vol 6, Iss 4, Pp 169-171 (2022) |
Druh dokumentu: | article |
ISSN: | 2468-600X 31459889 |
DOI: | 10.1016/j.ihjccr.2022.09.008 |
Popis: | The ChAdOx1 nCoV-19 adenoviral vector-based vaccine was the first to be approved against COVID-19 in India. Vaccine induced thrombotic thrombocytopenia (VITT) is a rare but serious adverse effect of the ChAdOx1 nCoV-19 vaccine, causing widespread thrombosis and thrombocytopenia. A 22-year-old patient, who had undergone mechanical mitral valve replacement, presented to us one week after administration of 1st dose of the ChAdOx1 nCoV-19 Coronavirus vaccine with acute prosthetic heart valve thrombosis (PVT). Laboratory investigations revealed thrombocytopenia and high D-Dimer levels, suggestive of probable VITT. In this report, we highlight the importance of identification of VITT as a cause of PVT and discuss management options. |
Databáze: | Directory of Open Access Journals |
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