RETROSPECTIVE ANALYSIS OF BREAST CANCER CASES AND SURGICAL TREATMENT IN A PERIOD OF TEN YEARS

Autor: Prakash Sayami, B M Singh, Y Singh, R Timila, U Shrestha, G Sayami, J K Chaudhari
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Zdroj: Journal of Nepal Medical Association, Vol 40, Iss 139 (2003)
Druh dokumentu: article
ISSN: 0028-2715
1815-672X
DOI: 10.31729/jnma.826
Popis: Retrospective analysis of 321 cases of breast cancer diagnosed in T. U Teaching Hospital in a period of 10 years, from May, 1991 to April, 2000 was carried out. There were 317 cases (98.8%) females and 4 cases males (1.2%). The youngest patient was 22 year old female and oldest patient was 92 year old female. The most common age group according to frequency was in forties (34.6%) followed by in thirties (25.5 %). Mean duration of symptoms before coming to doctor was 8.3 months and mean size of tumor was 6 cm. Out of 317 females, 310(97.2%) were married and average number of children was 3. Out of 289 cases diagnosed as malignancy with fine needle aspiration cytology (FNAC) 279 (96.5%) was also diagnosed as malignancy in biopsy and the remaining 10 cases as non malignant diseases were diagnosed as malignancy in biopsy with a false negative rate of 3.5%. The histological types of breast cancer cases were Infiltrating Ductal Carcinoma 280 cases (87.2%), Medullary Carcinoma 11 cases (3.4%), Infiltrating Lobular Carcinoma 5 cases (1.6%), Mucinous Carcinoma 4 cases (1.2%), Sarcoma 4 cases (1.2%), Squamous Cell Carcinoma 4 cases (1.2%), Papillary Carcinoma 3 cases (0.9%), Tubular Carcinoma 2 cases, Adenosquamous Carcinoma 2 cases (0.6%), Intraductal Carcinoma 2 cases (0.6%) and Non-Hodgkins Lymphoma 1 case. Out of 305 operated cases, the types of operation performed was Modified Radical Mastectomy in 208 cases (68 %) and palliative mastectomy in 72 cases (23.5%), only lumpectomy in 24 cases (7.9%) and others in 2 cases. Among 246 cases with available axillary lymph node biopsy, there was metastatic diseases in 146 cases (60%) of cases. The Breast cancer was diagnosed in advanced stages in 63% of cases. Stage IIIA (24%), Stage IIIB (21.5%) and Stage IV (17.4%). Breast cancers were diagnosed in advanced stages in below 40 age group in 65 out of 90 cases (72.2 % ) compared to137 out of 231 cases ( 59.3 % ) in above 40 age group. Key Words: Breast cancer, Advanced stage, FNAC, Surgery.
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