Hyperammonemic Encephalopathy and Lipid Dysmetabolism in a Critically Ill Patient after A Short Course of Amiodarone

Autor: Cappe Maximilien, Hantson Philippe, Komuta Mina, Vincent Marie-Françoise, Laterre Pierre-François, Ould-Nana Ismaïl
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: The Journal of Critical Care Medicine, Vol 5, Iss 4, Pp 161-165 (2019)
Druh dokumentu: article
ISSN: 2393-1817
2019-0026
16271114
DOI: 10.2478/jccm-2019-0026
Popis: The case is reported of a 39-year-old severely obese woman who developed acute metabolic disorders after the administration of a short course of intravenous amiodarone. The main biological features were hypertriglyceridemia, hypoglycaemia, hyperlactatemia and hyperammonemia; all were reversible after amiodarone discontinuation. There was an associated rise in liver enzymes. However, the influence of co-factors on these metabolic disorders, such as acquired carnitine deficiency, severe obesity, a long-term course of pancreatitis, and abdominal infections, could not be excluded.
Databáze: Directory of Open Access Journals