| Autor: |
Yuan Liu, Haydn Kissick, Viraj A Master, Mehmet Asim Bilen, Dylan Martini, Lauren Yantorni, Sarah Caulfield, Bassel Nazha, Omer Kucuk, Deepak Ravindranathan, Kenneth Ogan, Jacqueline T Brown, Julie M Shabto, Emilie Elise Hitron, Greta Anne Russler, Shreyas Subhash Joshi, Bradley C Carthon, Wayne B Harris |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2051-1426 |
| DOI: |
10.1136/jitc-2021-002851 |
| Popis: |
Background The modified Glasgow Prognostic Score (mGPS) is a composite biomarker that uses albumin and C reactive protein (CRP). There are multiple immune checkpoint inhibitor (ICI)-based combinations approved for metastatic renal cell carcinoma (mRCC). We investigated the ability of mGPS to predict outcomes in patients with mRCC receiving ICI.Methods We retrospectively reviewed patients with mRCC treated with ICI as monotherapy or in combination at Winship Cancer Institute between 2015 and 2020. Overall survival (OS) and progression-free survival (PFS) were measured from the start date of ICI until death or clinical/radiographical progression, respectively. The baseline mGPS was defined as a summary score based on pre-ICI values with one point given for CRP>10 mg/L and/or albumin |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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