Detection of invasive Bartonella infections with next-generation sequencing of microbial cell-free DNA

Autor: Fernando H Centeno, Ahmed M. Hamdi, Todd M. Lasco, Mayar Al Mohajer
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Antimicrobial Stewardship & Healthcare Epidemiology, Vol 4 (2024)
Druh dokumentu: article
ISSN: 2732-494X
DOI: 10.1017/ash.2024.16
Popis: We report 9 patients with invasive Bartonella infections, including 5 with endocarditis, who were diagnosed with microbial cell-free DNA next-generation sequencing and Bartonella serology studies. Diagnosis with plasma mcfDNA NGS enabled a faster clinical and laboratory diagnosis in 8 patients. Prompt diagnosis impacted antibiotic management in all 9 patients.
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