| Autor: |
Catherine M. Herzog, Fasil Aklilu, Demeke Sibhatu, Dereje Shegu, Redeat Belaineh, Abde Aliy Mohammed, Menbere Kidane, Claudia Schulz, Brian J. Willett, Sarah Cleaveland, Dalan Bailey, Andrew R. Peters, Isabella M. Cattadori, Peter J. Hudson, Hagos Asgedom, Joram Buza, Mesfin Sahle Forza, Tesfaye Rufael Chibssa, Solomon Gebre, Nick Juleff, Ottar N. Bjørnstad, Michael D. Baron, Vivek Kapur |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2399-3642 |
| DOI: |
10.1038/s42003-024-06619-2 |
| Popis: |
Abstract Peste des petits ruminants virus (PPRV) is a multi-host pathogen with sheep and goats as main hosts. To investigate the role of cattle in the epidemiology of PPR, we simulated conditions similar to East African zero-grazing husbandry practices in a series of trials with local Zebu cattle (Bos taurus indicus) co-housed with goats (Capra aegagrus hircus). Furthermore, we developed a mathematical model to assess the impact of PPRV-transmission from cattle to goats. Of the 32 cattle intranasally infected with the locally endemic lineage IV strain PPRV/Ethiopia/Habru/2014 none transmitted PPRV to 32 co-housed goats. However, these cattle or cattle co-housed with PPRV-infected goats seroconverted. The results confirm previous studies that cattle currently play a negligible role in PPRV-transmission and small ruminant vaccination is sufficient for eradication. However, the possible emergence of PPRV strains more virulent for cattle may impact eradication. Therefore, continued monitoring of PPRV circulation and evolution is recommended. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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