Clastogenic and cytotoxic effects of aerial parts’ aqueous extract of Synedrella nodiflora (L.) Gaertn. on Wistar rat bone marrow cells

Autor:	Saumabha Chatterjee, Sanjib Ray
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Apoptosis Clastogenic Cytotoxic Synedrella nodiflora Genotoxic Anticancer Biology (General) QH301-705.5 Cytology QH573-671
Zdroj:	Caryologia, Vol 72, Iss 3 (2019)
Druh dokumentu:	article
ISSN:	0008-7114 2165-5391
DOI:	10.13128/caryologia-770
Popis:	Synedrella nodiflora is a traditionally used medicinal plant. The aim of the present study was to analyze the clastogenic and cytotoxic effects (CCEs) of aerial parts’ aqueous extract of S. nodiflora (AAESN) on Wistar rat bone marrow cells (WRBMCs). The CCEs of AAESN were analyzed with light and fluorescence microscopes respectively. The data indicate a dose-dependent (100-500 mg/kg body weight [bw]) increase in the aberrant cell frequencies, chromosomal structural aberrations and a significant (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/4ee799b6e8e948a380363f308727d4b1 Zobrazit plný text záznamu View record in DOAJ