Autor: |
Subrat Kumar Bhattamisra, Vivian Lee Yean Yan, Chin Koh Lee, Chew Hui Kuean, Mayuren Candasamy, Yun Khoon Liew, Priyadarshi Soumyaranjan Sahu |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Journal of Traditional and Complementary Medicine, Vol 9, Iss 3, Pp 206-214 (2019) |
Druh dokumentu: |
article |
ISSN: |
2225-4110 |
DOI: |
10.1016/j.jtcme.2018.05.001 |
Popis: |
Geraniol, an active constituent of rose and palmarosa essential oils, possesses several pharmacological properties, including antioxidant, antibacterial and antiulcer activity. Geraniol was therefore investigated for its antiulcer and anti-Helicobacter pylori activity in rats. Ulcers were induced by injecting acetic acid into the sub-serosal layer of the stomach followed by orogastric inoculation of H. pylori for 7 days. Geraniol (15 and 30 mg/kg), vehicle and a standard drug combination (amoxicillin, 50 mg/kg; clarithromycin, 25 mg/kg and omeprazole, 20 mg/kg) were administered twice daily for 14 days. All the parameters were measured at the end of treatment. The ulcer index was significantly (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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