Change the preprocedural fasting policy for contrast-enhanced CT: results of 127,200 cases

Autor: Heng Liu, Li Zhao, Junling Liu, Fang Lan, Li Cai, Jingqin Fang, Xue Li
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Insights into Imaging, Vol 13, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 1869-4101
DOI: 10.1186/s13244-022-01173-z
Popis: Abstract Objectives To analyze the relationship between the dietary preparation status prior to contrast-enhanced CT (CECT) and adverse drug reactions (ADR) and emetic complications. Methods Non-emergency adult patients who underwent routine CECT in our hospital from January 2019 to December 2020 were retrospectively analyzed. Stratified dietary preparation regimens were implemented for different clinical scenarios. The relationship between actual dietary preparation status and ADR and emetic complications was analyzed. Results A total of 127,200 cases were enrolled, including 49,676 cases in the fasting group (57 years ± 13, 56.79% men) and 77,524 cases in the non-fasting group (60 years ± 13, 54.55% men). No statistical difference was found in the overall incidence of ADR (0.211% vs. 0.254%, p = 0.126) or emetic complications (0.030% vs. 0.046%, p = 0.158) between the two groups, and no aspiration pneumonia or death occurred. For patients with an ICM-ADR history, the ADR incidence in non-fasting group was significantly lower than fasting group (2.424% vs. 12.371%, p = 0.002). For patients with hypertension, injection dose ≥ 100 mL, injection rate ≥ 5 mL/s, and Iopromide 370 usage, non-fasting was associated with higher ADR incidence (p
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