Myogenin level tends to decrease in adult male cigarette smokers
| Autor: | Augustine Chinedu Ihim, Patrick O. Manafa, Vincent T. Ekechukwu, Manafa I. Vera, Victor N. Chukwudi, Sabina O. Ogbuowelu |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Universa Medicina, Vol 39, Iss 3 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1907-3062 2407-2230 |
| DOI: | 10.18051/UnivMed.2020.v39.178-183 |
| Popis: | Background The World Health Organization has warned that cigarette smoking is an avoidable risk factor for endothelial injury. Myogenin might play a role in muscle metabolism and energy utilization. Electrolytes and minerals are involved in most cellular activities. The objective of this study was to compare myogenin and electrolyte levels between adult male cigarette smokers (CS) and non-smokers (NS). Methods A cross-sectional study was conducted involving 90 subjects, consisting of 55 CS and 35 NS. The sandwich enzyme-linked immunosorbent assay was used to determine myogenin levels while the ion-selective electrode method was used to determine electrolyte levels. The levels of sodium, potassium, and chloride and the body mass index (BMI) were measured. Mann-Whitney and independent t-test were used to analyse the data. Results The BMI of CS was significantly lower than that of NS (p < 0.05). The mean serum levels of sodium (145.23 ± 1.87), potassium (4.00 ± 0.31) and chloride (103.95 ± 1.60) were significantly higher in the CS than in the NS (these being 142.38 ± 2.49, 3.83 ± 0.33, and 101.48 ± 2.08, respectively) (p |
| Databáze: | Directory of Open Access Journals |
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