Personalized immunoglobulin aptamers for detection of multiple myeloma minimal residual disease in serum

Autor: Claudia Tapia-Alveal, Timothy R. Olsen, Tilla S. Worgall
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-020-01515-x
Popis: Tapia-Alveal, Olsen and Worgall develop a novel strategy for patient-specific multiple myeloma diagnostics platform using DNA aptamers. The high affinity DNA aptamers enabled detection of minimal residual disease (MRD) when conventional MRD methods assessed complete remission and are adaptable to multiple diagnostic formats including point-of-care devices.
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