Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms

Autor:	TianRong Ma, XiaoLei Xue, Hui Tian, XinXiu Zhou, JunKe Wang, ZhiWen Zhao, MingFei Wang, JiYuan Song, RenXiang Feng, Leping Li, Changqing Jing, Feng Tian
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Gut microbiota Intestinal motility Metabolites Postoperative ileus Probiotics Review Medicine
Zdroj:	Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Druh dokumentu:	article
ISSN:	1479-5876
DOI:	10.1186/s12967-023-04215-2
Popis:	Abstract Gut microbiota is closely related to human health and disease because, together with their metabolites, gut microbiota maintain normal intestinal peristalsis. The use of antibiotics or opioid anesthetics, or both, during surgical procedures can lead to dysbiosis and affect intestinal motility; however, the underlying mechanisms are not fully known. This review aims to discuss the effect of gut microbiota and their metabolites on postoperative intestinal motility, focusing on regulating the enteric nervous system, 5-hydroxytryptamine neurotransmitter, and aryl hydrocarbon receptor.
Databáze:	Directory of Open Access Journals
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