Impact of dexamethason

Autor: Zahra Basirat, Mahtab Zeinalzadeh, Treza Mahouti, Masoumeh Golsorkhtabaramiri
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Middle East Fertility Society Journal, Vol 21, Iss 3, Pp 184-188 (2016)
Druh dokumentu: article
ISSN: 1110-5690
DOI: 10.1016/j.mefs.2016.01.001
Popis: Objective: Infertile women with polycystic ovary (PCOs) involve with anovulatory cycles. Various adjuvant treatments have been suggested to improve ovarian response in these patients. In this study, we aimed to evaluate the role of dexamethasone in the outcome of IVF/ICSI in PCOs infertile women. Study design: 129 PCOs infertile women undergone IVF/ICSI were enrolled for this single blind clinical trial study in 2012–2013. Setting: Fatemezahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran. Method: 43 patients who underwent IVF received dexamethasone (0.5 mg, 4 tab/day) in the treatment group and 74 patients were considered as the placebo group. Main outcome measure: Pregnancy rate was compared between the two groups. In addition, number of dominant follicle, oocytes retrieved, embryos transferred, and number of gonadotropin ampoule were evaluated. Results: The pregnancy rate in the group receiving dexamethasone was 17.5% significantly higher versus 4.3% in the placebo group (P
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