Changes in pain following bilateral intermittent theta-burst, transcranial magnetic stimulation for depression: A retrospective chart review

Autor: Sawmmiya Kirupaharan, Roumen Milev, Joanne Bressee, Sonya Kelso, Scott Duggan, Felicia Iftene, Tim V. Salomons, Wilma Hopman, Ian Gilron
Jazyk: English<br />French
Rok vydání: 2024
Předmět:
Zdroj: Canadian Journal of Pain, Vol 8, Iss 1 (2024)
Druh dokumentu: article
ISSN: 24740527
2474-0527
DOI: 10.1080/24740527.2023.2300026
Popis: Introduction Pain management in patients with chronic pain and comorbid depression is challenging and understudied. There is interest in intermittent theta-burst stimulation (iTBS), a new modality of repetitive transcranial magnetic stimulation (rTMS). This retrospective review describes changes in pain, anxiety and depression throughout iTBS treatment at the dorsolateral prefrontal cortex (DLPFC).Methods A retrospective chart review was conducted of patients who underwent their first acute series of iTBS treatments at the DLPFC for depression at a single institution between 2020 and 2023. Data on depression, anxiety, and pain were collected throughout iTBS treatment using the Beck Depression Inventory–II (BDI-II; higher scores indicate worse depression) and visual analogue scale (VAS; 0–100, higher scores indicate worse pain, anxiety, and depression). Nonparametric tests were used for all analyses.Results Of 104 patients, 52 reported moderate pain at baseline (50.0%). Median BDI-II scores decreased from 38.0 (interquartile range [IQR] = 29.0–44.0) to 24.0 (IQR = 9.0–36.0) from pre- to posttreatment (P
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