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Rushika Saksena,1 Monika Matlani,1 Vineeta Singh,2 Amit Kumar,2 Anupam Anveshi,1 Dilip Kumar,3 Rajni Gaind1 1Department of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, Delhi, India; 2Cell Biology Laboratory and Malaria Parasite Bank, National Institute of Malaria Research, Delhi, India; 3Department of Internal Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, Delhi, India Background: Concurrent dengue and mixed malaria infections in a single patient present with overlapping clinical manifestations which pose a diagnostic challenge and management dilemma in areas of common endemicities. Methods: We report a case of a young male who tested positive for both Plasmodium vivax and Plasmodium falciparum along with dengue infection. He showed signs of early treatment failure to artemisinin combination therapy (artesunate with sulfadoxine+pyrimethamine). Molecular analysis for the drug resistance genes viz: chloroquine resistance (pfcrt), multidrug resistance (pfmdr-1), sulfadoxine (pfdhps), pyrimethamine (pfdhfr), and artemisinin resistance (keltch 13) was performed.Results: A rise in parasitemia from |
