Evaluating Efficacy of Dynamic MR Perfusion Imaging in Soft Tissue Tumors

Autor: Idris Ozdas, Muhammet Firat Oztepe, Nil Tokgoz, Murat Ucar
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Current Research in MRI, Vol 3, Iss 2, Pp 43-48 (2024)
Druh dokumentu: article
ISSN: 2822-2318
DOI: 10.5152/CurrResMRI.2024.24101
Popis: Objective: The aim of this study was to assess the effectiveness of dynamic contrast-enhanced (DCE) MRI perfusion parameters and signal intensity–time curves in distinguishing between benign and malignant soft tissue tumors. Methods: The study included 51 patients with soft tissue tumors who underwent DCE MRI at 3.0 T. Among these patients, 30 had benign tumors, while 21 had malignant tumors. Perfusion parameters such as k-trans, kep, Ve, and iAUC were measured. Calculations were performed at the most contrast-enhanced areas of the lesions using circular regions of interest measuring 0.2-0.4 cm². The findings were illustrated using signal intensity–time (SIT) curves, which were categorized into 5 types for evaluation. Results: In the benign group, 19 out of 30 lesions (63.3%) showed contrast enhancement patterns corresponding to type 1-2 SIT curves, and 11 out of 30 lesions (36.7%) exhibited patterns corresponding to type 3-4-5 SIT curves. In contrast, all 21 malignant lesions (100%) displayed type 3-4-5 patterns. Mean values of K-trans (P < .001), Ve (P=.004), and iAUC (P
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