Prognostic impact of ARHGAP43(SH3BP1) in acute myeloid leukemia

Autor: Li Yang, Qiang Xu, Junnan Li
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of the Formosan Medical Association, Vol 123, Iss 9, Pp 992-1003 (2024)
Druh dokumentu: article
ISSN: 0929-6646
DOI: 10.1016/j.jfma.2024.04.002
Popis: Background: Acute myeloid leukemia (AML) is a hematological malignancy with a heterogeneous prognosis. Novel markers are required to accurately assess the prognosis and formulate treatment plans. Methods: The association of ARHGAP family genes with prognostic value in acute myeloid leukemia (AML) was assessed using public databases (CCLE, GEPIA, TCGA, and GEO). Results: Elevated expression of ARHGAP43 (SH3BP1) was associated with poor prognosis in patients with acute myeloid leukemia. ARHGAP43 (SH3BP1) expression was higher in the poor/adverse prognosis (P
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