Case Report: Omicron BA.2 Subvariant of SARS-CoV-2 Outcompetes BA.1 in Two Co-infection Cases

Autor: Marija Gjorgjievska, Sanja Mehandziska, Aleksandra Stajkovska, Slavica Pecioska-Dokuzovska, Anica Dimovska, Idriz Durmish, Sara Ismail, Teodora Pavlovska, Antonija Stojchevska, Haris Amedi, Jasna Andonova, Marija Nikolovska, Sara Velickovikj, Zan Mitrev, Ivan Kungulovski, Goran Kungulovski
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Genetics, Vol 13 (2022)
Druh dokumentu: article
ISSN: 1664-8021
DOI: 10.3389/fgene.2022.892682
Popis: Trends from around the world suggest that the omicron BA.2 subvariant is increasing in proportion to the original BA.1 subvariant. Here we report two cases of co-infection with omicron BA.1 and omicron BA.2 in co-exposed individuals. In both individuals, genome sequencing and/or S-gene specific PCR identified omicron BA.1 at early time-points, which was replaced by omicron BA.2 at later time-points of the infection. The timeline of our data supports the proposition that BA.2 outcompetes BA.1 in a real-life scenario, and in time becomes the dominant variant in the upper respiratory tract of the host.
Databáze: Directory of Open Access Journals