Automating the PathLinker app for Cytoscape [version 1; referees: 2 approved]

Autor: Li Jun Huang, Jeffrey N. Law, T. M. Murali
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: F1000Research, Vol 7 (2018)
Druh dokumentu: article
ISSN: 2046-1402
DOI: 10.12688/f1000research.14616.1
Popis: PathLinker is a graph-theoretic algorithm originally developed to reconstruct the interactions in a signaling pathway of interest. It efficiently computes multiple short paths within a background protein interaction network from the receptors to transcription factors (TFs) in a pathway. Since December 2015, PathLinker has been available as an app for Cytoscape. This paper describes how we automated the app to use the CyRest infrastructure and how users can incorporate PathLinker into their software pipelines.
Databáze: Directory of Open Access Journals