Association of whole grains intake and the risk of digestive tract cancer: a systematic review and meta-analysis

Autor: Xiao-Feng Zhang, Xiao-Kai Wang, Yu-Jun Tang, Xiao-Xian Guan, Yao Guo, Jian-Ming Fan, Ling-Ling Cui
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nutrition Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Druh dokumentu: article
ISSN: 1475-2891
DOI: 10.1186/s12937-020-00556-6
Popis: Abstract Background Several epidemiological studies have investigated the association between whole grains intake and digestive tract cancer risk; however, the results are still controversial. The purpose of this meta-analysis was to assess the association. Methods Studies published before March 2020 were searched in database and other sources. The risk ratio (RR) with the 95% confidence interval (CI) were pooled using fix or random-effects models. Results This meta-analysis included 34 articles reporting 35 studies, 18 studies of colorectal cancer, 11 studies of gastric cancer and 6 studies of esophagus cancer, involving 2,663,278 participants and 28,921 cases. Comparing the highest-intake participants with the lowest-intake participants for whole grains, we found that the intake of whole grains were inversely related to colorectal cancer (RR = 0.89, 95% CI: 0.84–0.93, P
Databáze: Directory of Open Access Journals
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