A Pancreatic Polypeptide-Producing Pancreatic Tumor Causing WDHA Syndrome

Autor:	Vera Amrilleva, Emily P. Slater, Jens Waldmann, Dorothee Bonorden, Volker Fendrich
Jazyk:	angličtina
Rok vydání:	2008
Předmět:	Endocrine pancreatic tumor WDHA syndrome Pancreatic polypeptide Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Case Reports in Gastroenterology, Vol 2, Iss 2, Pp 238-243 (2008)
Druh dokumentu:	article
ISSN:	1662-0631 00014273
DOI:	10.1159/000142739
Popis:	We report the case of a 46-year-old female patient with WDHA (watery diarrhea/hypokalemia/achlorhydria) syndrome caused by a pancreatic polypeptide-producing tumor in the head of the pancreas. Whereas VIP and other pancreatic endocrine hormones were in the normal range, only serum levels of pancreatic polypeptide were elevated. Imaging studies identified a pancreatic tumor in the head of the gland. After laparotomy, the tumor of 3 cm in size was enucleated. Final pathology documented a pancreatic endocrine tumor with immunohistochemical staining demonstrating the presence of pancreatic polypeptide. The patient remained cured after a follow-up of more than three years. The present case illustrates that, although rare, WDHA syndrome may be associated with a pancreatic polypeptide-secreting endocrine tumor of the pancreas.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/4e2241c553874f72b5fdf06d6cad7fe9 Zobrazit plný text záznamu View record in DOAJ