Case Report: Mineralized Pulmonary Artery Thrombi in Two Dogs Treated for Meningoencephalitis of Unknown Origin

Autor: Suzanne Rosen, Leontine Benedicenti, Scott Petesch, Jennifer Reetz, Evelyn Marie Galban
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Veterinary Science, Vol 7 (2020)
Druh dokumentu: article
ISSN: 2297-1769
DOI: 10.3389/fvets.2020.569597
Popis: Meningoencephalitis of unknown origin (MUO) is a relatively common and very serious canine neurologic condition, which is typically associated with a poor long term prognosis despite treatment. This case series chronicles two dogs diagnosed with MUO who were treated with long term corticosteroids and cytosine arabinoside and lived well-beyond the typical survival time for this condition. Both eventually succumbed to respiratory signs associated with mineralized thrombi in their pulmonary arteries. Adverse effects from the two drugs used for treatment are reviewed in order to propose a possible mechanism to explain how long term use of these medications could result in such a phenomenon.
Databáze: Directory of Open Access Journals