Correction of Immune Disorders in Patients with Abdominal Sepsis

Autor: O. A. Dolina, L. O. Shkrob
Jazyk: English<br />Russian
Rok vydání: 2011
Předmět:
Zdroj: Общая реаниматология, Vol 7, Iss 1 (2011)
Druh dokumentu: article
ISSN: 1813-9779
2411-7110
DOI: 10.15360/1813-9779-2011-1-55
Popis: Objective: to estimate the diagnostic value of cerebral oximetry during cardiosurgical operations and to elaborate principles of the prevention of postperfusion neurological dysfunction. Subjects and methods. Four hundred and sixty-one patients operated on under extracorporeal circulation (EC) were examined. Cerebral oxygenation (CO) was monitored in all the patients. Pre-, intra-, and postoperative data were analyzed. Results. Two groups of patients were identified: 1) 148 patients with a reduced CO of lower than 45% during EC and 2) 313 patients without reduced CO. Group 1 was found to have lower preoperative levels of hemoglobin and packed cell volume and baseline reduced bilateral CO, more frequent concomitant brachiocephalic artery (BCA) stenoses of more than 50%, more detectable dyscirculatory encephalopathy (DEP) in the history. Group differences were found in the level of hemoglobin and packed cell volume, oxygen delivery, and PaCO2 during EC and there was a relationship of the rate of CO reductions to the type of cardioplegia. There were also group differences in the magnitude of CO reduction versus the baseline levels. In the postoperative period, encephalopathy (EP) was manifested in 24 (16.3%) and 12 (3.8%) patients in Groups 1 and 2, respectively (p
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