Changing Drivers of Mortality Among Patients Referred for Cardiac Stress Testing

Autor: Alan Rozanski, MD, Heidi Gransar, MS, Sean W. Hayes, MD, John D. Friedman, MD, Louise E.J. Thomson, MBChB, Daniel S. Berman, MD
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 5, Iss 3, Pp 560-573 (2021)
Druh dokumentu: article
ISSN: 2542-4548
DOI: 10.1016/j.mayocpiqo.2020.08.013
Popis: Objective: To identify temporal shifts in coronary artery disease (CAD) risk factor profiles, clinical parameters, and corresponding mortality rates among patients referred for radionuclide stress testing over 22 years. Patients and Methods: We assessed 39,750 patients with suspected CAD (“diagnostic” patients) and 10,982 patients with known CAD who underwent radionuclide stress testing between January 2, 1991, and December 31, 2012, and were followed up for at least 5 years (median, 12.7 years). Results: Among both diagnostic patients and those with known CAD, there was a marked temporal decline in typical angina and myocardial ischemia. However, several risk factors for disease progressively increased, including diabetes, obesity, and hypertension. In addition, the need to perform pharmacological testing in lieu of exercise increased markedly between the first and fourth epochs among both diagnostic patients (from 26.5% [1634 of 6176] to 53.0% [5781 of 10,908]; P
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