Prolonged waitlisting is associated with mortality in extracorporeal membrane oxygenation-supported heart transplantation candidatesCentral MessagePerspective

Autor: Taylor Nordan, BS, Andre C. Critsinelis, MD, Amanda Vest, MBBS, MPH, Yijing Zhang, MPH, Frederick Y. Chen, MD, PhD, Gregory S. Couper, MD, Masashi Kawabori, MD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JTCVS Open, Vol 12, Iss , Pp 234-254 (2022)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2022.09.010
Popis: Objective: Heart transplantation (HTx) candidates supported with venoarterial extracorporeal membrane oxygenation (ECMO) may be listed at highest status 1 but are at inherent risk for ECMO-related complications. The effect of waitlist time on postlisting survival remains unclear in candidates with ECMO support who are listed using the new allocation system. Methods: Adult candidates listed with ECMO for a first-time, single-organ HTx from October 18, 2018, to March 21, 2021, in the Scientific Registry of Transplant Recipients database were included and stratified according to waitlist time (≤7 vs ≥8 days). Postlisting outcomes were compared between cohorts. Results: Among 175 candidates waitlisted for ≤7 days, 162 (92.6%) underwent HTx whereas 13 (7.4%) died/deteriorated compared with 41 (57.8%) and 21 (29.6%) of the 71 candidates waitlisted for ≥8 days, respectively (P
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