Cost-effectiveness of implant movement analysis in aseptic loosening after hip replacement: a health-economic model

Autor: Davide Lovera, Olof Sandberg, Maziar Mohaddes, Hanna Gyllensten
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cost Effectiveness and Resource Allocation, Vol 21, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1478-7547
DOI: 10.1186/s12962-023-00498-w
Popis: Abstract Objective To investigate the cost-effectiveness of using Implant Movement Analysis (IMA) to follow up suspected aseptic loosening when the diagnosis after an initial X-ray is not conclusive, compared with a diagnostic pathway with X-ray follow-up. Methods A health-economic model in the form of a decision tree was developed using quality-adjusted life years (QALY) from the literature, cost-per-patient data from a university hospital and the probabilities of different events from expert physicians’ opinions. The base case incremental cost-effectiveness ratio (ICER) was compared with established willingness-to-pay thresholds and sensitivity analyses were performed to account for assumptions and uncertainty. Results The base case ICER indicated that the IMA pathway was cost effective (SEK 99,681, compared with the SEK 500,000 threshold). In the sensitivity analysis, the IMA pathway remained cost effective during most changes in parameters. ICERs above the threshold value occurred in cases where a larger or smaller proportion of people receive immediate surgery. Conclusion A diagnostic pathway using IMA after an inconclusive X-ray for suspected aseptic loosening was cost effective compared with a pathway with X-ray follow-up.
Databáze: Directory of Open Access Journals
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