Cerebral Malaria: Case Report

Autor: Serhat Tokgöz, Esra Eruyar, Ayşegül Öğmegül, İbrahim Erayman
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Türk Nöroloji Dergisi, Vol 16, Iss 3, Pp 149-153 (2010)
Druh dokumentu: article
ISSN: 1301-062X
Popis: Cerebral malaria is a rare complication caused by Plasmodium infection. Capillary blockage caused by infected erythrocytes, microglia activation and apoptosis of astrocytes as a result of cytokine leakage to the parenchyma are cited in the pathogenesis. Recently, a concept has evolved that metabolic changes in the brain in malaria infection may also be responsible for the epilepsy and encephalopathy pathogenesis. A 25-year-old male was admitted to our clinic for seizures and encephalopathy. The patient, diagnosed with cerebral malaria, recovered with antiedema, antiepileptic and antimalarial therapy. The pathophysiology and clinical and laboratory findings are discussed in light of the literature.
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