Characteristics of DNA-AuNP networks on cell membranes and real-time movies for viral infection

Autor: Chunmei Li, Linling Zheng, Xiaoxi Yang, Xiaoyan Wan, Wenbi Wu, Shujun Zhen, Yuanfang Li, Lingfei Luo, Chengzhi Huang
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Data in Brief, Vol 6, Iss , Pp 652-660 (2016)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2015.12.044
Popis: This data article provides complementary data for the article entitled “DNA-AuNP networks on cell membranes as a protective barrier to inhibit viral attachment, entry and budding” Li et al. (2016) [1]. The experimental methods for the preparation and characterization of DNA-conjugated nanoparticle networks on cell membranes were described. Confocal fluorescence images, agarose gel electrophoresis images and hydrodynamic diameter of DNA-conjugated gold nanoparticle (DNA-AuNP) networks were presented. In addition, we have prepared QDs-labeled RSV (QDs-RSV) to real-time monitor the RSV infection on HEp-2 cells in the absence and presence of DNA-AuNP networks. Finally, the cell viability of HEp-2 cells coated by six types of DNA-nanoparticle networks was determined after RSV infection. Keywords: DNA-AuNP networks, Cell membrane, Viral infection, Inhibition
Databáze: Directory of Open Access Journals