Koninginins X-Z, Three New Polyketides from Trichoderma koningiopsis SC-5

Autor:	Weiwei Peng, Jianbing Tan, Zihuan Sang, Yuantao Huang, Li Xu, Yuting Zheng, Siyu Qin, Haibo Tan, Zhenxing Zou
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Trichoderma koningiopsis endophytic fungi secondary metabolites polyketide antifungal activity Organic chemistry QD241-441
Zdroj:	Molecules, Vol 28, Iss 23, p 7848 (2023)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules28237848
Popis:	Koninginins X-Z (1–3), three novel polyketides, were isolated from the solid fermentation of the endophytic fungus Trichoderma koningiopsis SC-5. Their structures, including the absolute configurations, were comprehensively characterized by a combination of NMR spectroscopic methods, HRESIMS, 13C NMR, DFT GIAO 13C NMR, and electronic circular dichroism calculations as well as single crystal X-ray diffraction. In addition, all the compounds were evaluated for antifungal activity against Candida albicans.
Databáze:	Directory of Open Access Journals
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