The relationship between systemic inflammation index, systemic immune-inflammatory index, and inflammatory prognostic index and 90-day outcomes in acute ischemic stroke patients treated with intravenous thrombolysis

Autor: Fei Ma, Lulu Li, Liang Xu, Jiacheng Wu, Aimei Zhang, Junqi Liao, Jingyi Chen, Yunze Li, Li Li, Zhaoyao Chen, Wenlei Li, Qing Zhu, Yuan Zhu, Minghua Wu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1742-2094
DOI: 10.1186/s12974-023-02890-y
Popis: Abstract Background and purpose To explore the association of systemic inflammatory index (SIRI), systemic immune-inflammatory index (SII) and inflammatory prognosis index (IPI) with 90d outcomes in patients with acute ischemic stroke (AIS) after intravenous thrombolysis. Methods The patients who underwent intravenous thrombolysis were enrolled in the present study from September 2019 to December 2022. According to the relevant blood indexes obtained in 24 h after admission, the corresponding values of SIRI, SII and IPI were calculated. The correlation among SIRI, SII, IPI, and admission NIHSS scores was examined by Spearman correlation analysis. ROC curve analysis was conducted to determine the optimal cut-off value of SIRI, SII, IPI, and their corresponding sensitivity and specificity to evaluate their predictive value on admission for poor prognosis. To investigate whether high SIRI, SII, and IPI were independent predictors of poor outcomes within 90 days, variables with P-value
Databáze: Directory of Open Access Journals
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