Evaluation of Lower Urinary Tract Functions in Diabetic Patients

Autor: Ümit Eskidemir, Adnan Şimşir, Ilgın Yıldırım Şimşir, Fuat Kızılay, Ceyhun Özyurt
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Urological Surgery, Vol 6, Iss 1, Pp 46-53 (2019)
Druh dokumentu: article
ISSN: 2148-9580
DOI: 10.4274/jus.galenos.2018.2314
Popis: Objective:In this study, we aimed to investigate the effect of diabetes-related metabolic changes and chronic complications on lower urinary tract (LUT) functions.Materials and Methods:The study included 286 adult patients with type 1 and type 2 diabetes mellitus (DM). All patients’ demographic data, diabetes-specific history, laboratory and physical examination findings were recorded. All the data were compared with uroflowmetric parameters and the scores of questionnaires used for evaluation of LUT symptoms and functions.Results:In the presence of diabetic peripheral neuropathy (DPN), average urinary flow rate (Qave), International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) score and the Overactive Bladder-questionnaire Short Form (OAB-q SF) score were significantly affected. In the presence of stage 3 or over diabetic nephropathy (DN), ICIQ-SF score was significantly higher. Also, in elderly group, Qave and OAB-q SF score were significantly affected. The Qave was lower both in patients who underwent any surgery due to diabetic complications and in patients with DM-related diseases. Qave and OAB-q SF score were significantly lower in males. Type 2 DM was associated with postvoid residual (PVR) increase and Qave decrease. Poor glycemic control was associated with lower OAB-q SF score. Finally, vitamin D deficiency was found to be associated with an increase in PVR volume.Conclusion:The present study showed that DPN, stage 3 or over DN, aging, DM-related diseases and surgeries, male gender, type 2 DM, poor glycemic control and vitamin D deficiency cause a tendency to develop any kind of LUT dysfunction.
Databáze: Directory of Open Access Journals