Transcriptional response to an alternative diet on liver, muscle, and rumen of beef cattle

Autor: Anna Carolina Fernandes, Antonio Reverter, Kate Keogh, Pâmela Almeida Alexandre, Juliana Afonso, Julio Cesar Pascale Palhares, Tainã Figueiredo Cardoso, Jessica Moraes Malheiros, Jennifer Jessica Bruscadin, Priscila Silva Neubern de Oliveira, Gerson Barreto Mourão, Luciana Correia de Almeida Regitano, Luiz Lehmann Coutinho
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-63619-2
Popis: Abstract Feed cost represents a major economic determinant within cattle production, amounting to an estimated 75% of the total variable costs. Consequently, comprehensive approaches such as optimizing feed utilization through alternative feed sources, alongside the selection of feed-efficient animals, are of great significance. Here, we investigate the effect of two diets, traditional corn-grain fed and alternative by-product based, on 14 phenotypes related to feed, methane emission and production efficiency and on multi-tissue transcriptomics data from liver, muscle, and rumen wall, derived from 52 Nellore bulls, 26 on each diet. To this end, diets were contrasted at the level of phenotype, gene expression, and gene-phenotype network connectivity. As regards the phenotypic level, at a P value
Databáze: Directory of Open Access Journals
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