Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study

Autor:	Vincenzo Accurso, Marco Santoro, Simona Raso, Angelo Davide Contrino, Paolo Casimiro, Florinda Di Piazza, Alessandro Perez, Antonio Russo, Sergio Siragusa
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Splenomegaly Polycythemia Vera essential thrombocythemia Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Hematology Reports, Vol 11, Iss 4 (2019)
Druh dokumentu:	article
ISSN:	2038-8322 2038-8330
DOI:	10.4081/hr.2019.8281
Popis:	Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with these diseases. We aimed to study the impact that such alteration has on thrombotic risk and on the survival of patients with essential thrombocythemia and patients with Polycythemia Vera (PV). We studied the relationship between splenomegaly (and its grade), thrombosis and survival in 238 patients with et and 165 patients with PV followed at our center between January 1997 and May 2019.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/4d6ee256346148dabe43cd1d2e146c9c Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF