Neutrophil-to-Lymphocyte Ratio in Adult Patients with Anemia: A Hospital-Based Cross-Sectional Study

Autor: Nilu Manandhar, Kushal Bhattarai, Krishant Bhandari
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Karnali Academy of Health Sciences, Vol 6, Iss 3 (2023)
Druh dokumentu: article
ISSN: 2616-0064
2676-1327
DOI: 10.61814/jkahs.v6i3.851
Popis: Background: Neutrophil-to-lymphocyte ratio, a well-defined marker of immunity, is raised in many conditions which are characterized by abnormal inflammatory and immunological responses. Anemia of chronic disease, the most prevalent type in hospitalized patients, is a dominant clinical picture in protracted stimulation of immunity. This study aimed to assess the neutrophil-to-lymphocyte ratio in adult participants with anemia and to compare of the ratio with non-anemic participants. Methods: In a cross-sectional study conducted in the Department of Clinical Physiology of Karnali Academy of Health Sciences, Teaching Hospital, Jumla, Karnali Province, Nepal, in the months of August, 2023, data on clinico-demographic variables were retrieved from the laboratory information system of hospital records of February–March, 2023. From the hematological parameters retrieved, the status of anemia and the neutrophil-to-lymphocyte ratio were calculated. Results: After scrutiny of the laboratory records of 1421 adult patients, with 69.7% (N=990) female, the prevalence of anemia was 12.4% (N=176) and the median neutrophil-to-lymphocyte ratio was 2.21 (IQR: 1.41–3.75). The median neutrophil-to-lymphocyte ratio was significantly greater in the anemic participants among the overall (p
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