Azole-resistant Candida blankii as a newly recognized cause of bloodstream infection

Autor: A. Al-Haqqan, N. Al-Sweih, S. Ahmad, S. Khan, L. Joseph, S. Varghese, Z. Khan
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: New Microbes and New Infections, Vol 26, Iss , Pp 25-29 (2018)
Druh dokumentu: article
ISSN: 2052-2975
DOI: 10.1016/j.nmni.2018.06.008
Popis: Candida blankii is a newly recognized human pathogen. Here we describe a case of bloodstream infection in a preterm neonate. The yeast was repeatedly isolated from blood, and its identity was confirmed by PCR sequencing of rDNA. Additionally, C. blankii DNA was detected directly in a blood sample. The isolates initially developed pink colonies on CHROMagar Candida which later turned into dark metallic blue similar to Candida tropicalis. Inaccurate identification by the VITEK 2 yeast identification system as Stephanoascus ciferrii and intrinsic resistance to fluconazole (MIC 12–16 μg/mL) underscore the need for its accurate identification for appropriate therapeutic management. Keywords: Azole resistance, Candida blankii, molecular identification, neonate
Databáze: Directory of Open Access Journals