A unique presentation of 5-fluorouracil (5-FU) induced cerebral encephalopathy

Autor:	Shailendra S Naik, Ilavarasi Vanidassane, Ekta Dhamija, Atul Sharma
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	chemotherapy drug-induced encephalopathy encephalopathy 5-fluorouracil Medical physics. Medical radiology. Nuclear medicine R895-920
Zdroj:	Indian Journal of Radiology and Imaging, Vol 30, Iss 02, Pp 214-217 (2020)
Druh dokumentu:	article
ISSN:	0971-3026 1998-3808 67992579
DOI:	10.4103/ijri.IJRI_17_19
Popis:	5-Fluorouracil (5-FU), a commonly used antimetabolite and antineoplastic agent, has been approved for the treatment of various cancers. It is associated with systemic side-effects such as gastrointestinal problems, neutropenia. 5-FU-related encephalopathy is very rarely reported. Imaging with computed tomography (CT) and magnetic resonance imaging (MRI) plays a key role in diagnosing and monitoring the changes. Since the prognosis of cerebral involvement is usually good if recognized and treated in time, the reporting radiologist and treating physician should be familiar with them. We present a rare case of 5-FU-induced encephalopathy that was diagnosed based on her clinical and MRI findings and managed successfully.
Databáze:	Directory of Open Access Journals
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