Indices of metal proteins (transferrin, ceruloplasmin) in overweight and obese children
| Autor: | Tamila V. SOROKMAN, Snizhana V. SOKOLNYK, Alexandra-Maria V. POPELYUK, Sergii O. SOKOLNYK, Olena V. MAKAROVA, Volodymyr V. BEZRUK |
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| Jazyk: | English<br />French |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Archives of the Balkan Medical Union, Vol 54, Iss 2, Pp 300-306 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1584-9244 2558-815X |
| DOI: | 10.31688/ABMU.2019.54.2.12 |
| Popis: | Introduction. A progressive increase of obesity prevalence, both among adults and children, is observed in many countries. Today, obesity is seen as a chronic systemic inflammation with low activity. Currently, new data are available about the biological and clinical significance of metal proteins in the inflammatory processes. The objective was to study the transferrin and ceruloplasmin indices in overweight and obese children. Material and methods. We have examined children with excess body weight (EBW, 30 children), obesity (40 children) and 30 healthy children aged 13-18 years. The evaluation included history, anthropometric data (height, body weight, body mass index, waist-to-thigh ratio – WTR), serum glucose, insulin, HOMA-IR calculation, transferrin (TF) and ceruloplasmin (CP). For statistical analysis of the results, statistic modules of Statistica v.6.0, MedStat and on-line SISA calculator were used. Results. In a total sample of 325 children, excess body weight was observed in 75 (23.1%) cases and obesity in 68 (13.6%) children. Boys prevailed, with 40 (53.3%) cases of EBW among those and 38 (55.8%) with obesity. The content of TF and CP in children aged 16-18 years was higher (28.1±0.8 mg/dL and 3.90±0.70 g/L, n = 22, p |
| Databáze: | Directory of Open Access Journals |
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