| Autor: |
Xianyue Ren, Xiaojing Yang, Bin Cheng, Xiaozhong Chen, Tianpeng Zhang, Qingmei He, Bin Li, Yingqin Li, Xinran Tang, Xin Wen, Qian Zhong, Tiebang Kang, Musheng Zeng, Na Liu, Jun Ma |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms14053 |
| Popis: |
HOPX is a transcription factor epigenetically silenced in several cancers. Here the authors, by analysing methylation profiles, identify HOPX as a suppressor of metastasis in nasopharyngeal carcinoma: mechanistically HOPX inhibitsSNAILtranscription through deacetylation-mediated silencing. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
