Dysglycemia in adults at risk for or living with non-insulin treated type 2 diabetes: Insights from continuous glucose monitoring

Autor: Souptik Barua, Ashutosh Sabharwal, Namino Glantz, Casey Conneely, Arianna Larez, Wendy Bevier, David Kerr
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: EClinicalMedicine, Vol 35, Iss , Pp 100853- (2021)
Druh dokumentu: article
ISSN: 2589-5370
DOI: 10.1016/j.eclinm.2021.100853
Popis: Background: Continuous glucose monitoring (CGM) has demonstrable benefits for people living with diabetes, but the supporting evidence is almost exclusively from White individuals with type 1 diabetes. Here, we have quantified CGM profiles in Hispanic/Latino adults with or at-risk of non-insulin treated type 2 diabetes (T2D). Methods: 100 participants (79 female, 86% Hispanic/Latino [predominantly Mexican], age 54·6 [±12·0] years) stratified into (i) at risk of T2D, (ii) with pre-diabetes (pre-T2D), and (iii) with non-insulin treated T2D, wore blinded CGMs for 2 weeks. Beyond standardized CGM measures (average glucose, glucose variability, time in 70–140 mg/dL and 70–180 mg/dL ranges), we also examined additional CGM measures based on the time of day. Findings: Standardized CGM measures were significantly different for participants with T2D compared to at-risk and pre-T2D participants (p
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