Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes

Autor: Diana A. Díaz-Rizzolo, Leinys S. Santos Baez, Collin J. Popp, Rabiah Borhan, Ana Sordi-Guth, Emily N. C. Manoogian, Satchidananda Panda, Bin Cheng, Blandine Laferrère
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-4 (2024)
Druh dokumentu: article
ISSN: 2044-4052
DOI: 10.1038/s41387-024-00347-6
Popis: Abstract This study investigates the impact of habitual late calorie intake on glucose metabolism in adults with overweight or obesity and diet or metformin-controlled prediabetes or type 2 diabetes independently of body weight, fat mass, energy intake or diet composition. Participants (n = 26) were classified as Later Eaters (LE) if ≥45% daily calories were consumed after 5 pm and Early Eaters (EE) if not, based on daily caloric intake assessed over 2-wk. EE and LE did not differ in anthropometrics or daily energy intake, but LE consumed more carbohydrates (p = 0.038) and fats (p = 0.039) after 5 pm. Fasting glucose, insulin, and C-peptide did not differ between groups but LE exhibited higher glucose concentrations after an oral glucose tolerance test (p = 0.001), even after adjusting for body weight, fat mass, energy intake and diet composition (p
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