Visual evoked potentials show strong positive association with intracranial pressure in patients with cryptococcal meningitis

Autor: Marcelo Adriano da Cunha Silva Vieira, Maria do Amparo Salmito Cavalcanti, Dorcas Lamounier Costa, Kelsen Dantas Eulálio, Otoni Cardoso do Vale, Chrystiany Placido de Brito Vieira, Carlos Henrique Nery Costa
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Arquivos de Neuro-Psiquiatria, Vol 73, Iss 4, Pp 309-313 (2015)
Druh dokumentu: article
ISSN: 1678-4227
0004-282X
DOI: 10.1590/0004-282X20150002
Popis: Objective : To verify the relationship between intracranial pressure and flash visual evoked potentials (F-VEP) in patients with cryptococcal meningitis. Method The sample included adults diagnosed with cryptococcal meningitis admitted at a reference hospital for infectious diseases. The patients were subjected to F-VEP tests shortly before lumbar puncture. The Pearsons linear correlation coefficient was calculated and the linear regression analysis was performed. Results : Eighteen individuals were subjected to a total of 69 lumbar punctures preceded by F-VEP tests. At the first lumbar puncture performed in each patient, N2 latency exhibited a strong positive correlation with intracranial pressure (r = 0.83; CI = 0.60 - 0.94; p < 0.0001). The direction of this relationship was maintained in subsequent punctures. Conclusion : The intracranial pressure measured by spinal tap manometry showed strong positive association with the N2 latency F-VEP in patients with cryptococcal meningitis.
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