Anti-synthetase syndrome in a patient with recurrent episodes of pulmonary embolism: a case report

Autor: Moemen Eltelbany, Yuting Huang, Preetinder Sandhu, Abdul Akbaryeh, Nzube Iloh, Dena H. Tran, Jamal Mikdashi, Iram Bakhtawar
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Community Hospital Internal Medicine Perspectives, Vol 10, Iss 3, Pp 255-257 (2020)
Druh dokumentu: article
ISSN: 2000-9666
20009666
DOI: 10.1080/20009666.2020.1769421
Popis: Anti-synthetase syndrome (ASS) is characterized by myositis that is associated with progressive interstitial lung disease (ILD). The prognosis of the disease is affected by the type and degree of pulmonary involvement. We report a rare case of ASS with positive Anti-EJ antibody presenting with a combination of recurrent deep vein thrombosis/pulmonary embolism (DVT/PE) and progressive ILD. This case demonstrates the delayed diagnosis of ASS and the association of thromboembolic disease and ASS. Physicians should have a high index of suspicion for ASS, as early diagnosis and management alters the morbidity and prognosis of patients with ASS. Abbreviations ASS: Anti-synthetase syndrome; Ab: Antibody; Ag: Antigen; ANA: Anti-nuclear antibodies; CK: Creatine kinase; CRP: C-reactive protein; DVT: Deep Vein Thrombosis; ESR: Erythrocyte Sedimentation Rate; ILD: Interstitial lung disease; PE: Pulmonary Embolism; CTA: CT Angiography
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje