Autor: |
Fabrizio Fabrizi, Maria F. Donato, Luca Nardelli, Federica Tripodi, Francesca Zanoni, Giuseppe Castellano |
Jazyk: |
Spanish; Castilian |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Nefrología, Vol 44, Iss 4, Pp 486-495 (2024) |
Druh dokumentu: |
article |
ISSN: |
0211-6995 |
DOI: |
10.1016/j.nefro.2024.01.002 |
Popis: |
Introduction and aim: Hepatitis C virus infection and chronic kidney disease are major public health issues all over the world. It has been suggested a role of HCV as a risk factor for the development and progression of chronic kidney disease (defined by reduced glomerular filtration rate and/or detectable proteinuria) in the general population but conflicting findings have been given. Material and methods: A systematic review of the published medical literature was conducted to assess whether positive HCV serologic status is associated with greater rate of proteinuria in the adult general population. We used a random-effect model to generate a summary estimate of the relative risk of proteinuria with HCV across the published studies. Results: We identified 23 studies (n = 198,967 unique patients) and performed separate meta-analyses according to the study design. Overall effect estimate was significant in cross-sectional (OR, 1.47, 95%CI, 1.3; 1.66) (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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