Phyllodes Tumor of the Breast: 307 Treated Cases, the Largest Mexican Experience at a Single Breast Disease Institution

Autor: Eva Ruvalcaba-Limón, Josefina Jiménez-López, Verónica Bautista-Piña, Julio Ramírez-Bollas, Flavia Morales-Vásquez, Carlos Domínguez-Reyes, Antonio Maffuz-Aziz, Sergio Rodríguez-Cuevas
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Iranian Journal of Pathology, Vol 11, Iss 4, Pp 399-408 (2016)
Druh dokumentu: article
ISSN: 1735-5303
2345-3656
Popis: Background: Phyllodes tumor (PT) of the breast in Hispanic patients is more frequently reported with large tumors and with more borderline/malignant subtypes compared with other populations. The objective of this study was to describe characteristics of patients with PT and to identify differences among subtypes in a Mexican population. Methods: A retrospective study was conducted on patients with PT. Sociodemographic, histopathologic, and treatment characteristics were compared among subtypes, including only surgically treated cases due the complete surgical-specimen study requirement for appropriate WHO classification. Results: During 10 years, 346 PT were diagnosed; only 307 were included (305 patients), with a mean age of 41.7 yr. Self-detected lump took place in 91.8%, usually discovered 6 months previously, with median tumor size of 4.5 cm. Local wide excisions were done in 213 (69.8%) and mastectomies in 92 (30.1%). Immediate breast reconstruction took place in 38% and oncoplastic procedures in 23%. PT were classified as benign in 222 (72.3%) cases, borderline in 50 (16.2%), and malignant in 35 (11.4%), with pathological tumor size of 4.2, 5.4, and 8.7 cm, respectively (P
Databáze: Directory of Open Access Journals